

As a result, the heart muscle can't get the blood or oxygen it needs. As it grows, less blood can flow through the arteries. This is due to the buildup of cholesterol and other material, called plaque, on their inner walls. It is the leading cause of death in the United States in both men and women.cad happens when the arteries that supply blood to heart muscle become hardened and narrowed. Coronary artery disease (cad) is the most common type of heart disease.Build-up of fatty material and calcium deposition in the arterial wall resulting in partial or complete occlusion of the arterial lumen.These include following a healthy diet, getting regular exercise, maintaining a healthy weight, quitting smoking, and managing stress. Treatments include medicines, and medical procedures or surgery. Many people don't know they have the disease until they have a medical emergency.a physical examination, imaging and other diagnostic tests can tell if you have it. When they are blocked, you can suffer from numbness, pain and sometimes infections.Ītherosclerosis usually doesn't cause symptoms until it severely narrows or totally blocks an artery. These arteries are in your arms, legs and pelvis. When they are blocked you can suffer a stroke. These arteries supply blood to your brain. When they are blocked, you can suffer angina or a heart attack. These arteries supply blood to your heart. That limits the flow of oxygen-rich blood to your body and can lead to serious problems, including Over time, plaque hardens and narrows your arteries. Plaque is a sticky substance made up of fat, cholesterol, calcium, and other substances found in the blood. Atherosclerosis is a disease in which plaque builds up inside your arteries.It is a form of myocardial ischemia (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels. An imbalance between myocardial functional requirements and the capacity of the coronary vessels to supply sufficient blood flow.Age, lifestyle, diet, and gene related degeneration of arteries due to deposition of lipoid plaques (atheromas) on inner arterial walls main cause of coronary artery disease, a leading cause of death.

A thickening and loss of elasticity of the walls of arteries that occurs with formation of atherosclerotic plaques within the arterial intima.The risk of coronary artery disease is increased by having a family history of coronary artery disease before age 50, older age, smoking tobacco, high blood pressure, high cholesterol, diabetes, lack of exercise, and obesity.

The disease may cause chest pain, shortness of breath during exercise, and heart attacks. Coronary artery disease is usually caused by atherosclerosis (a build up of fatty material and plaque inside the coronary arteries).
